Simmons Cancer Institute (SCI) at Southern Illinois University will host its 22nd annual Denim & Diamonds fundraiser at 6 p.m. on Saturday, October 8, at the Crowne Plaza Springfield, 3000 S. Dirksen Parkway. The glitzy event features auctions, raffles, live entertainment and fine dining. Guests are encouraged to dress in formal attire, denim or mix-and-match for a fashionable combination. The live and silent auction items include vacation-home getaways, gourmet dinners, sporting event tickets, original artwork, one-of-a-kind jewelry and much more. Dinner will be followed by live music from