Trial
Psychiatry

Click: Study to Evaluate the Efficacy and Safety of a Digital Therapeutic as an Adjunct to Standard-of-Care Antipsychotic Therapy in Adult and Late Adolescent Participants with Experiential Negative Symptoms of Schizophrenia

Active recruiting

CT-155-R-001: The purpose of this study is to investigate if digital therapeutics (a moblie software application) can help treat certain symptoms of schizophrenia. 

News

Adams research efforts earn 2022 Toth Award

The Research Policy Committee honored Kristal Adams with the 2022 Frank J. Toth Award, the highest recognition for SIU School of Medicine research support personnel. Adams is a clinical research program director in the Center for Clinical Research.
News

Adams research efforts earn 2022 Toth Award

The Research Policy Committee honored Kristal Adams with the 2022 Frank J. Toth Award, the highest recognition for SIU School of Medicine research support personnel. Adams is a clinical research program director in the Center for Clinical Research.
Trial
Neurology

A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Phase 3 Study to Evaluate the Safety, Tolerability, and Efficacy of XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures

Active recruiting

The primary objective is to assess the effect of XEN1101 versus placebo on reducing PGTCS frequency in subjects with PGTCS.

Trial
Neurology

A Randomized, Double-Blind, Placebo-Controlled, Multicenter Phase 3 Study to Evaluate the Safety, Tolerability, and Efficacy of XEN1101 as Adjunctive Therapy in Focal-Onset Seizures

Active recruiting

The primary objective of this study is to assess the effect of XEN1101 versus placebo on reducing focal seizure frequency.

Trial
Neurology

An Open-Label, Multicenter, Outpatient Extension Study to Evaluate the Safety and Tolerability of Staccato Alprazolam in Study Participants 12 Years of Age and Older with Stereotypical Prolonged Seizures

Active recruiting

The primary endpoint of this study is to evaluate the long-term safety and tolerability of Staccato alprazolam.

Trial
Neurology

A Double-Blind, Randomized, Placebo-Controlled, Multicenter, Outpatient, Parallel-Group Study to Assess the Efficacy and Safety of Staccato Alprazolam in Study Participants 12 Years of Age and Older with Stereotypical Prolonged Seizures

Active recruiting

The purpose of this study is to compare the success of a single admnistration of Staccato alprazolam compared with placebo in rapidly terminating a seizure episode within 90seconds after IMP administration.

General Results
News

New program puts community health workers at ground level

Establishing roots Community health worker Kaye Barnes sports a purple SIU Medicine T-shirt to complement her green thumb as she works in Springfield’s community gardens. A native of the city’s north side, she feels at home both tilling the soil or working in the trenches for her clients in the school of medicine’s Office of Community Care (OCC). Barnes is a diabetes lifestyle educator, a nationally certified nutrition coach and has a master’s degree in library science. In the summer of 2023, she created and launched Operation Taproot, a new program she hopes will grow and flourish across
News

New program puts community health workers at ground level

Establishing roots Community health worker Kaye Barnes sports a purple SIU Medicine T-shirt to complement her green thumb as she works in Springfield’s community gardens. A native of the city’s north side, she feels at home both tilling the soil or working in the trenches for her clients in the school of medicine’s Office of Community Care (OCC). Barnes is a diabetes lifestyle educator, a nationally certified nutrition coach and has a master’s degree in library science. In the summer of 2023, she created and launched Operation Taproot, a new program she hopes will grow and flourish across
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