Trial
Psychiatry

A prospective multicenter study to characterize the natural history of tardive dyskinesia (TD) and investigate the real-world effectiveness of deutetrabenazine on the multidimensional impact of TD

Active recruiting

What is the effectiveness of deutetrabenazine treatment on the multidimensional impact of TD movements on individuals’ lives?

Trial
Psychiatry

A Randomized, Double-Blind, Placebo-Controlled Trial of REL-1017 as an Adjunctive Treatment for Major Depressive Disorder (RELIGHT)

Active recruiting

The primary efficacy endpoint is the change in the Montgomery-Asberg Depression Rating Scale (MADRS) total score from Baseline to Day 28 for REL-1017 as compared to placebo.

Trial
Psychiatry

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Valbenazine as Adjunctive Treatment in Subjects with Schizophrenia

Active recruiting

The primary objective for this study is to evaluate the effect of adjunctive valbenazine versus placebo on symptoms of schizophrenia in subjects who have inadequate response to antipsychotic treatment.

Trial
Psychiatry

The RECOVER sUb-study, which leverages quaNtitative and Credible research tOols from Verily, will providE assessment measuRes for depressive episodes. (The UNCOVER Study)

Active recruiting

The primary objective of this study is to collect both active and passive study watch and phone application data, which aims to capture mental health status, in subjects participating in the RECOVER clinical trial (A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression).

Trial
Psychiatry

A PRospective, Multi-cEnter, Randomized Controlled Blinded Trial DemOnstrating the Safety and Effectiveness of VNS Therapy® System as AdjunctivE Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression (RECOVER)

Active recruiting

The primary objective of this study is to determine whether active VNS Therapy treatment is superior to a no stimulation control in producing at least a 50% reduction in baseline depressive symptom severity, based on Montgomery Åsberg Depression Rating Scale (MADRS) total score, at 12 months from randomization.

Trial
Psychiatry

Click Therapeutics CT-155-R-01

Active recruiting

To evaluate the efficacy and safety of CT-155 in reducing experiential negative symptoms, compared with a Digital Control, in adult and late adolescent participants diagnosed with schizophrenia.

News

A day in the life of an SIU Medicine resident physician

Life as a resident physician is not for the faint of heart. They must balance patient care, ongoing medical education and training requirements. Resident well-being is part of an ongoing national discussion as medical programs seek to reduce stress and prevent burnout among trainees. Dr. Julio Mendoza Estrada is a second-year internal medicine resident. We followed him on a typical clinic day to learn how he handles the stresses of resident life. “On average I work anywhere from 60 to 70 hours a week. Study hours every day are variable, depending on how busy that day was. But I'll often study
News

A day in the life of an SIU Medicine resident physician

Life as a resident physician is not for the faint of heart. They must balance patient care, ongoing medical education and training requirements. Resident well-being is part of an ongoing national discussion as medical programs seek to reduce stress and prevent burnout among trainees. Dr. Julio Mendoza Estrada is a second-year internal medicine resident. We followed him on a typical clinic day to learn how he handles the stresses of resident life. “On average I work anywhere from 60 to 70 hours a week. Study hours every day are variable, depending on how busy that day was. But I'll often study
News

Turning ripples into waves

Dr. Kari Wolf oversees state’s new behavioral health training center Kari Wolf, MD , has never been afraid of making waves. The chair of SIU Medicine’s Department of Psychiatry was born in Evanston, Illinois, and raised in Iowa where she experienced her first opportunity to challenge the status quo and make a meaningful impact. At 12-years-old, Wolf fearlessly stood up for what she believed in when she chose, along with another student from rural Iowa, to file a federal lawsuit against the Iowa Girls High School Athletic Union, asserting that the state's 6-on-6 basketball rules violated the U
News

Turning ripples into waves

Dr. Kari Wolf oversees state’s new behavioral health training center Kari Wolf, MD , has never been afraid of making waves. The chair of SIU Medicine’s Department of Psychiatry was born in Evanston, Illinois, and raised in Iowa where she experienced her first opportunity to challenge the status quo and make a meaningful impact. At 12-years-old, Wolf fearlessly stood up for what she believed in when she chose, along with another student from rural Iowa, to file a federal lawsuit against the Iowa Girls High School Athletic Union, asserting that the state's 6-on-6 basketball rules violated the U
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