Preparing only the GRC form pages and neglecting to prepare the research proposal portion of the application; i.e., the protocol addressing specific aims, background and significance, preliminary studies, research design and methods, and literature review. Lack of a clear hypothesis. Discrepancies between specific aims and methodology; research design inadequate to accomplish specific aims. Relationship of study design to data analysis not clearly expressed. Inadequate justification of relevance of data to be collected in study. Lack of adequate explanation of terminology and proposed