Trial
Neurology

UCB EP0162: A Double-Blind, Randomized, Placebo-Controlled, Multicenter, Outpatient, Parallel-Group Study to Assess the Efficacy and Safety of Staccato Alprazolam in Study Participants 12 Years of Age and Older with Stereotypical Prolonged Seizures

Active recruiting
The purpose of this study is to compare the success of a single admnistration of Staccato alprazolam compared with placebo in rapidly terminating a seizure episode within 90seconds after IMP administration.
Trial
Trial
Neurology

ADCS Benfo: A Seamless Phase 2A-Phase 2B Randomized Double-Blind Placebo-Controlled Trial to Evaluate the Safety and Efficacy of Benfotiamine in Patients with Early Alzheimer’s Disease (BenfoTeam)

Active recruiting
The purpose of this study is to learn more about the safety, effectiveness and tolerability of the study drug called Benfotiamine, to determine whether it delays or slows the progression of the symptoms of early Alzheimer’s disease.
Trial
Internal Medicine

RECHARGE

Active recruiting
To compare the effect of percutaneous coronary intervention (PCI) vs coronary artery bypass grafting (CABG) on survival and improvement in quality-of-life (QOL) in women and minorities.
General Results

Neural Basis of Decisions current lab projects

Algorithmic basis of reward-based decisions in dynamic environment In probabilistic reward foraging task (Fig.1A) animals’ choices tend to reflect the previous rewards, in a way that biases animals’ future choices to options from which they recently received the rewards. In addition to the reward history effects, curiously animals choices also depend on the previous choices, phenomenon that is not easily explained by the current computational models (Fig.1B). We are formulating normative accounts of why choice history effects should persist in animals. The insight into this phenomenon may give
News

SIU medical student awarded national research fellowship for work on cancer-fighting immune cells

SPRINGFIELD, Ill. – Anjali Patel, a second-year medical student at Southern Illinois University School of Medicine, has been selected for the 2025 Carolyn L. Kuckein Student Research Fellowship by the Alpha Omega Alpha Honor Medical Society. The nationally competitive award supports medical students conducting original research in areas that advance clinical medicine and patient care. Patel’s project explores a novel approach to enhancing the effectiveness of natural killer (NK) cells in treating solid tumors. Her research aims to prevent immune suppression in the tumor environment by blocking
News

SIU medical student awarded national research fellowship for work on cancer-fighting immune cells

SPRINGFIELD, Ill. – Anjali Patel, a second-year medical student at Southern Illinois University School of Medicine, has been selected for the 2025 Carolyn L. Kuckein Student Research Fellowship by the Alpha Omega Alpha Honor Medical Society. The nationally competitive award supports medical students conducting original research in areas that advance clinical medicine and patient care. Patel’s project explores a novel approach to enhancing the effectiveness of natural killer (NK) cells in treating solid tumors. Her research aims to prevent immune suppression in the tumor environment by blocking
News

SIU medical student awarded national research fellowship for work on cancer-fighting immune cells

SPRINGFIELD, Ill. – Anjali Patel, a second-year medical student at Southern Illinois University School of Medicine, has been selected for the 2025 Carolyn L. Kuckein Student Research Fellowship by the Alpha Omega Alpha Honor Medical Society. The nationally competitive award supports medical students conducting original research in areas that advance clinical medicine and patient care. Patel’s project explores a novel approach to enhancing the effectiveness of natural killer (NK) cells in treating solid tumors. Her research aims to prevent immune suppression in the tumor environment by blocking
News

SIU medical student awarded national research fellowship for work on cancer-fighting immune cells

SPRINGFIELD, Ill. – Anjali Patel, a second-year medical student at Southern Illinois University School of Medicine, has been selected for the 2025 Carolyn L. Kuckein Student Research Fellowship by the Alpha Omega Alpha Honor Medical Society. The nationally competitive award supports medical students conducting original research in areas that advance clinical medicine and patient care. Patel’s project explores a novel approach to enhancing the effectiveness of natural killer (NK) cells in treating solid tumors. Her research aims to prevent immune suppression in the tumor environment by blocking
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